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Mitral regurgitation, also known as mitral insufficiency or mitral incompetence, is the backward flow of blood from the left ventricle, through the mitral valve, and into the left atrium, when the left ventricle contracts, resulting in a systolic murmur radiating to the left armpit.
Mitral valve prolapse is frequently associated with mild mitral regurgitation, [15] where blood aberrantly flows from the left ventricle into the left atrium during systole. In the United States , MVP is the most common cause of severe, non-ischemic mitral regurgitation. [ 4 ]
Mitral regurgitation: the backflow of blood from the left ventricle into the left atrium, owing to insufficiency of the mitral valve; it may be acute or chronic, and is usually due to mitral valve prolapse, rheumatic heart disease, or a complication of cardiac dilatation. See also Mitral regurgitation.
Mitral regurgitation may be treated medically with vasodilators, diuretics, digoxin, antiarrhythmics, and chronic anticoagulation. [15] [16] Mild to moderate mitral regurgitation should be followed with echocardiography and cardiac stress test every 1–3 years. [15]
Mitral valve prolapse: This is the most common cause of late systolic murmurs. It can be heard best over the apex of the heart, usually preceded by clicks. The most common cause of mitral valve prolapse is "floppy" valve (Barlow's) syndrome. If the prolapse becomes severe enough, mitral regurgitation may occur.
Patients with mitral valve regurgitation typically have a holosystolic murmur, meaning it lasts for the duration of systole. Now even though we said that left-sided heart failure can cause mitral regurgitation, it also goes the other way, mitral regurgitation can be a cause of left-sided heart failure.
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