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Neuromodulation exists in the olfactory system and is responsible for neural plasticity and behavioural change in both mammals and insects. [4] In the context of olfactory memory, neuromodulators regulate storage of information in a way that maintains the significance of the olfactory experience. [4]
The olfactory bulb (Latin: bulbus olfactorius) is a neural structure of the vertebrate forebrain involved in olfaction, the sense of smell. It sends olfactory information to be further processed in the amygdala, the orbitofrontal cortex (OFC) and the hippocampus where it plays a role in emotion, memory and learning.
Mice form an olfactory memory which helps them define and react to the presence of pheromones. Humans have no VNO but still a level of communication through semiochemicals. These classes of pheromonal action are the opposite-sex attractants, the same-sex repellants (territorial markers), mother–infant bonding attractants and those modulating ...
Loss of olfactory function is also an early symptom of neurodegenerative diseases including Parkinson’s and Alzheimer’s, according to recent findings published in Neurology. It found that the ...
The third memory trace is the reduction of activity of the anterior-paired lateral neuron, which acts as a memory formation suppressor through one of its inhibitory GABAergic receptors. Decrease in calcium response of APL neurons and subsequent decrease in GABA release onto the mushroom bodies persisted up to 5 minutes after odor conditioning.
The olfactory sensory system is unique since the neurons in the olfactory bulb send their axons directly to the olfactory cortex, rather than to the thalamus first. Olfaction is also the only sense that is represented by the ipsilateral side of the brain. Damage to the olfactory bulb results in a loss of olfaction (the sense of smell).
The anterior olfactory nucleus is the memory hub for smell. [24] When different odor objects or components are mixed, humans and other mammals sniffing the mixture (presented by, e.g., a sniff bottle) are often unable to identify the components in the mixture even though they can recognize each individual component presented alone. [25]
The sense of smell is closely linked to memory and emotions because the olfactory system is connected to the brain's limbic system, which is involved in emotional processing and memory formation. This connection means that specific scents can trigger vivid memories and strong emotional responses.