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Due to the causal relationship of insufficient zinc levels to taste disorders, research has been conducted to test the efficacy of zinc supplementation as a possible treatment for dysgeusia. In a randomized clinical trial, fifty patients with idiopathic dysgeusia were given either zinc or a lactose placebo. [9]
While zinc supplementation may treat certain taste dysfunctions, there is a lack of evidence for treatment regarding hypogeusia and dysgeusia not caused by low zinc concentrations in the body. [6] While the mechanisms surrounding hypogeusia from PD are hypothesized, specific treatments are not researched enough. [3]
Low plasma zinc levels have been alleged to be associated with many psychological disorders. Schizophrenia has been linked to decreased brain zinc levels. [23] Evidence suggests that zinc deficiency could play a role in depression. [23] [24] [25] Zinc supplementation may be an effective treatment in major depression. [26] [27]
Mineral deficiency is a lack of the dietary minerals, the micronutrients that are needed for an organism's proper health. [1] The cause may be a poor diet, impaired uptake of the minerals that are consumed, or a dysfunction in the organism's use of the mineral after it is absorbed.
Ageusia (from negative prefix a-and Ancient Greek γεῦσις geûsis 'taste') is the loss of taste functions of the tongue, particularly the inability to detect sweetness, sourness, bitterness, saltiness, and umami (meaning 'savory taste'). It is sometimes confused with anosmia – a loss of the sense of smell.
Acrodermatitis enteropathica is an autosomal recessive metabolic disorder affecting the uptake of zinc through the inner lining of the bowel, the mucous membrane. It is characterized by inflammation of the skin ( dermatitis ) around bodily openings (periorificial) and the tips of fingers and toes (acral), hair loss ( alopecia ), and diarrhea .