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Erwin Chargaff (11 August 1905 – 20 June 2002) was an Austro-Hungarian-born American biochemist, writer, and professor of biochemistry at Columbia University medical school. [1] A Bucovinian Jew who emigrated to the United States during the Nazi regime, he penned a well-reviewed [ 2 ] [ 3 ] autobiography, Heraclitean Fire: Sketches from a ...
[1] [2] The 2005 NASA Authorization Act designated the American segment of the International Space Station as a national laboratory with the goal of increasing the use of the ISS by other federal agencies and the private sector. [3] Research on the ISS improves knowledge about the effects of long-term space exposure on the human body.
While the “Epoch of Reionization” sounds like the title of a sci-fi novel destined for a Hugo award, this very real era of the universe featured the first light from the very first stars.
The traditional model of the Big Bang. The use of only general relativity to predict what happened in the beginnings of the universe has been heavily criticized, as quantum mechanics becomes a significant factor in the high-energy environment of the earliest stage of the universe, and general relativity on its own fails to make accurate predictions.
However, Erwin Chargaff [5] showed that the four frequencies were not equal, with variations consistent between different studies. Specifically, according to his rules the correct relationship is G = C ≠ A = T.
An inhomogeneous cosmology is a physical cosmological theory (an astronomical model of the physical universe's origin and evolution) which, unlike the dominant cosmological concordance model, assumes that inhomogeneities in the distribution of matter across the universe affect local gravitational forces (i.e., at the galactic level) enough to skew our view of the Universe. [3]
The following table is a representative sample of Erwin Chargaff's 1952 data, listing the base composition of DNA from various organisms and support both of Chargaff's rules. [17] An organism such as φX174 with significant variation from A/T and G/C equal to one, is indicative of single stranded DNA.
The universe has been observed to be homogeneous and isotropic (i.e. is smoothly distributed) at very large scales, as is expected in a standard Big Bang or Friedmann-Lemaître-Robertson-Walker cosmology, and in most interpretations of the Lambda-Cold Dark Matter model.