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Benign Rolandic epilepsy or self-limited epilepsy with centrotemporal spikes (formerly benign childhood epilepsy with centrotemporal spikes (BECTS)) is the most common epilepsy syndrome in childhood. [ 1 ] [ 2 ] Most children will outgrow the syndrome (it starts around the age of 3–13 with a peak around 8–9 years and stops around age 14 ...
Kindling is a commonly used model for the development of seizures and epilepsy in which the duration and behavioral involvement of induced seizures increases after seizures are induced repeatedly. [1] Kindling is also referred as an animal visual model of epilepsy that can be produced by focal electrical stimulation in the brain.
Epileptogenesis is the gradual process by which a typical brain develops epilepsy. [1] Epilepsy is a chronic condition in which seizures occur. [2] These changes to the brain occasionally cause neurons to fire in an abnormal, hypersynchronous manner, known as a seizure. [3]
A spike-and-wave discharge is a regular, symmetrical, generalized EEG pattern seen particularly during absence epilepsy, also known as ‘petit mal’ epilepsy. [1] The basic mechanisms underlying these patterns are complex and involve part of the cerebral cortex , the thalamocortical network , and intrinsic neuronal mechanisms.
An EEG showing epilepsy right-hippocampal seizure onset An EEG showing epilepsy left-hippocampal seizure onset The hippocampus is one of the few brain regions where new neurons are generated. This process of neurogenesis is confined to the dentate gyrus. [ 150 ]
The condition causes a variety of symptoms, but usually includes some degree of epilepsy or recurring seizures, and often affects the brain's ability to function. Symptoms vary in severity; the condition is occasionally discovered as an incidentaloma when brain imaging performed for an unrelated problem and has no apparent ill effect on the ...