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Fel d 1 is a secretoglobin protein complex that, in cats, is encoded by the CH1 (chain 1/Fel d 1-A) and CH2 (chain 2/Fel d 1-B) genes. [2] [3] Among cats, Fel d 1 is produced largely in their saliva and by the sebaceous glands located in their skin. It is the primary allergen present on cats and kittens.
Fel d 1 is the most prominent cat allergen, accounting for 96% of human cat allergies. [4] The remaining cat allergens are Fel d 2–8, [5] with Fel d 4, a major urinary protein found in the saliva of cats, [6] occurring the most in humans among the other seven allergens. All cats produce Fel d 1, including hypoallergenic cats.
Fel d 1 was supposed to be put into two subfamilies: chain 1 in subfamily 4, and chain 2 in subfamily 5. [3] Although it is not mentioned in the 2011 update, InterPro matches suggest that CH1 is similar to 1B and CH2 is similar to 2B. [5] Extra computational research confirms the similarity, invalidating subfamilies 4 and 5 fully. [6]
Fel d1 is a protein primarily found in cat saliva and sebaceous glands. [17] Those with cat allergies may react to direct contact with Sphynx cats. [ 17 ] Even though reports exist that some people with allergies successfully tolerate Sphynx cats, they are fewer than those who have allergic reactions.
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Most had higher titres of antibodies against Fel d 4 than against Fel d 1, another prominent cat allergen. [13] Likewise, Equ c 1 ( Equus caballus allergen 1; Q95182 ) is the protein product of a horse Mup gene that is found in the liver, sublingual and submaxillary salivary glands.
The Albanian Wikipedia (Albanian: Wikipedia Shqip) is the Albanian language edition of Wikipedia started on 12 October 2003. As of 15 January 2025, the Wikipedia has 101,316 articles and is the 73rd-largest Wikipedia.
1'D1 ' 2-8-2 Steam locomotive 6 New, built in Poland with a top speed of 80 km/h and built in the same series as TKt48 class. Fleet number TKt 48.01-48.06 [5] In service until 1991. One locomotive is a monument in Tirana. [4] Status: scrapped, but one: 1951, 1952 106-002 106-003: Steam locomotive 2