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The vagus nerve is also responsible for regulating inflammation in the body, via the inflammatory reflex. [7] Efferent vagus nerve fibers innervating the pharynx and back of the throat are responsible for the gag reflex. In addition, 5-HT 3 receptor-mediated afferent vagus stimulation in the gut due to gastroenteritis is a cause of vomiting. [8]
Stimulation of the efferent vagus nerve slows heart rate, induces gastrointestinal motility, and inhibits TNF production in spleen. [1] Stimulation of the efferent pathway of the vagus nerve releases acetylcholine, the neurotransmitter which interacts with the α7 subunit of the nicotinic AChR (α7 nAChR). nAChR is expressed on the cell ...
Many or most cases are idiopathic. The most common known cause is autonomic neuropathy of the vagus nerve, which innervates the stomach. Uncontrolled diabetes mellitus is a frequent cause of this nerve damage, but trauma to the vagus nerve is also possible. Some cases may be considered post-infectious.
The inferior ganglion of the vagus nerve (also known as the nodose ganglion) is one of the two sensory ganglia of each vagus nerve (cranial nerve X). It contains neuron cell bodies of general visceral afferent fibers and special visceral afferent fibers. [1] It is situated within the jugular fossa just below the skull.
The mechanism of development of Cushing ulcers is thought to be due to direct stimulation of vagal nuclei as a result of increased intracranial pressure.Brain tumors, traumatic head injury, and other intracranial processes including infections, can cause increased intracranial pressure and lead to overstimulation of the vagus nerve. [3]
The nerve receives close attention from surgeons because the nerve is at risk for injury during neck surgery, especially thyroid and parathyroid surgery; as well as esophagectomy. [20] [4] Nerve damage can be assessed by laryngoscopy, during which a stroboscopic light confirms the absence of movement in the affected side of the vocal cords. The ...
In contrast, pseudobulbar palsy is a clinical syndrome similar to bulbar palsy but in which the damage is located in upper motor neurons of the corticobulbar tracts in the mid-pons (i.e., in the cranial nerves IX-XII), that is the nerve cells coming down from the cerebral cortex innervating the motor nuclei in the medulla.
The superior laryngeal nerve is a branch of the vagus nerve. It arises from the middle of the inferior ganglion of the vagus nerve and additionally receives a sympathetic branch from the superior cervical ganglion .