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  2. Rifampicin - Wikipedia

    en.wikipedia.org/wiki/Rifampicin

    It is also used as preventive treatment against Neisseria meningitidis (meningococcal) infections. Rifampicin is also recommended as an alternative treatment for infections by the tick-borne pathogens Borrelia burgdorferi and Anaplasma phagocytophilum when treatment with doxycycline is contraindicated, such as in pregnant women or in patients ...

  3. Meningococcal disease - Wikipedia

    en.wikipedia.org/wiki/Meningococcal_disease

    Meningococcal disease describes infections caused by the bacterium Neisseria meningitidis (also termed meningococcus). [1] It has a high mortality rate if untreated but is vaccine-preventable. [2] While best known as a cause of meningitis, it can also result in sepsis, which is an even more damaging and dangerous condition.

  4. Chemoprophylaxis - Wikipedia

    en.wikipedia.org/wiki/Chemoprophylaxis

    Chemoprevention or chemoprophylaxis refers to the administration of a medication for the purpose of preventing disease or infection. [1] [2] Antibiotics, for example, may be administered to patients with disorders of immune system function to prevent bacterial infections (particularly opportunistic infection). [3]

  5. Rifamycin - Wikipedia

    en.wikipedia.org/wiki/Rifamycin

    Rifamycins are particularly effective against mycobacteria, and are therefore used to treat tuberculosis, leprosy, and mycobacterium avium complex (MAC) infections. The rifamycin group includes the classic rifamycin drugs as well as the rifamycin derivatives rifampicin (or rifampin), rifabutin, rifapentine, rifalazil and rifaximin. Rifamycin ...

  6. Management of tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Management_of_tuberculosis

    Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.

  7. Meningitis - Wikipedia

    en.wikipedia.org/wiki/Meningitis

    Severe meningococcal and pneumococcal infections may result in hemorrhaging of the adrenal glands, leading to Waterhouse-Friderichsen syndrome, which is often fatal. [23] The brain tissue may swell, pressure inside the skull may increase and the swollen brain may herniate through the skull base.

  8. Neisseria meningitidis - Wikipedia

    en.wikipedia.org/wiki/Neisseria_meningitidis

    A meningococcal polysaccharide vaccine (MPSV4) has been available since the 1970s and is the only meningococcal vaccine licensed for people older than 55. MPSV4 may be used in people 2–55 years old if the MCV4 vaccines are not available or contraindicated. Two meningococcal conjugate vaccines (MCV4) are licensed for use in the U.S. The first ...

  9. rpoB - Wikipedia

    en.wikipedia.org/wiki/RpoB

    It is targeted by the rifamycin family of antibacterials, such as rifampin. [2] Mutations in rpoB that confer resistance to rifamycins do so by altering the protein's drug-binding residues, thereby reducing affinity for these antibiotics. [3] [4]

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