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In osteoarthritis, there is a loss of articular hyaluronic acid activity, likely contributing to pain and stiffness associated with the condition. Hyaluronic acid injections are an FDA-approved treatment for osteoarthritis of the knee, and are sometimes also used for other joints. However, the merits of HA injections are still disputed.
Illustration of a Hand affected by Rheumatoid arthritis. Rheumatoid Arthritis (RA) is an inflammatory disease that's caused by an autoimmune condition. The condition occurs when bodily cells begin to attack and target their own healthy joint tissues resulting in redness, inflammation, and pain.
Several approved drugs are being investigated as repurposed agents in the treatment of osteoarthritis such as liraglutide (anti-diabetic and anti-obesity drug: NCT02905864), Metformin (anti-diabetic drug: NCT04767841, NCT05034029), Zoledronic acid (anti-osteoporotic drug: NCT04303026), etc. [4] Paroxetine has been deemed to have DMOAD activity ...
The primary surgical treatment option of arthritis is joint replacement surgery known as arthroplasty. [92] Common joints that are replaced due to arthritis include the shoulder, hip, and knee. [92] Arthroscopic surgery for osteoarthritis of the knee provides no additional benefit to patients when compared to optimized physical and medical ...
Weight loss drugs like Ozempic and Wegovy may provide strong relief from severe osteoarthritis knee pain, ... is best known as a drug for the treatment of type 2 diabetes and obesity, ...
The use of diacerein is to be limited to treating symptoms of osteoarthritis affecting the hip or knee. Diacerein should not be administered during pregnancy and lactation. The PRAC concluded that the benefit-risk balance of diacerein-containing medicinal products remained favourable in the symptomatic treatment osteoarthritis, subject to the ...