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Carnosine (beta-alanyl-L-histidine) is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues. [citation needed] Carnosine was discovered by Russian chemist Vladimir Gulevich. [1] Carnosine is naturally produced by the body in the liver [2] from beta-alanine and histidine.
Zinc L-carnosine (beta-alanyl-L-histidinato zinc [1]) (N-(3-aminopropionyl)-L-histidinato zinc [2]), often simply called zinc carnosine, and also known as polaprezinc, [3] is a mucosal protective [4] [5] chelate compound of zinc and L-carnosine invented by Hamari Chemicals, Ltd. [6] [7] It is a quadridentate 1:1 complex of a polymeric nature. [6]
Sucralfate is used for the treatment of active duodenal ulcers not related to the use of nonsteroidal anti-inflammatory drugs (NSAIDs), as the mechanism behind these ulcers is due to acid oversecretion. [1] It is not FDA approved for gastric ulcers, but is widely used because of evidence of efficacy. [10]
The Shirley Temple mocktail was first created about a century ago, but its history, ingredients and recipe are up for debate, a cocktail professional told Fox News Digital.
When making beef bone broth, source knuckle, neck, or marrow bones (sometimes labeled as beef soup bones). For chicken bone broth, use chicken carcasses, necks, feet, or wings. Get the Recipe: Ham ...
It is a dimer, and hydrolyzes both carnosine and anserine, preferring dipeptides that have a histidine monomer in the C-terminus position. [ 11 ] [ 12 ] Tissue carnosinase is often considered a "nonspecific dipeptidase", [ 13 ] [ 15 ] based in part on its ability to hydrolyze a range of dipeptide substrates , including those belonging to ...