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  2. Adalimumab - Wikipedia

    en.wikipedia.org/wiki/Adalimumab

    The best-selling drugs list published by Genetic Engineering & Biotechnology News, shows that Humira occupied the #1 position for 2015 (US$14.012 billion) and 2016 (US$16.078 billion) [99] From 2012 until the US patent expired in 2016, Humira led the list of top-selling pharmaceutical products, and in 2016, it had US$16 billion of global sales ...

  3. TNF inhibitor - Wikipedia

    en.wikipedia.org/wiki/TNF_inhibitor

    A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their ...

  4. Management of Crohn's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Crohn's_disease

    Vedolizumab is a gut-selective, Alpha-4 Beta-7 anti-integrin, monoclonal antibody that was approved by the U.S. Food and Drug Administration to treat Crohn's disease in 2014. It is indicated for management of moderate-to-severe, active Crohn's disease patients and it works by inhibiting the trafficking of pro-inflammatory immune cells to the ...

  5. AbbVie's Humira Still a Growth Engine - AOL

    www.aol.com/news/2014-03-08-abbvies-humira-still...

    A recently published report by global pharma researcher Decision Resources suggests that forward growth in key European markets for AbbVie's flagship drug Humira, a treatment for autoimmune ...

  6. AbbVie's tight grip on Humira market raises concerns about ...

    www.aol.com/news/abbvies-tight-grip-humira...

    AbbVie’s top-selling arthritis drug Humira has held onto more than 80% of patients after facing nine lower-priced rivals in the U.S. in the last year, raising questions about whether the market ...

  7. Humira's Sales Will Decline -- and It's Fantastic News for AbbVie

    www.aol.com/news/humira-apos-sales-decline-apos...

    Even with falling sales, Humira should still rank as the top-selling drug in the world in 2024.

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