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In general, cytotoxic edema is linked to cell death in the brain through excessive cellular swelling. [1] During cerebral ischemia for example, the blood–brain barrier remains intact but decreased blood flow and glucose supply leads to a disruption in cellular metabolism and creation of energy sources, such as adenosine triphosphate (ATP). [1]
Cerebral edema is mainly classified into cytotoxic edema, vasogenic edema and interstitial edema. Cytotoxic edema affects both the white and gray matter and results from the swelling of cellular elements such as neurons, glia and endothelial cells. Vasogenic edema affects white matter and results from blood brain barrier (BBB) breakdown ...
High-altitude cerebral edema (HACE) is a medical condition in which the brain swells with fluid because of the physiological effects of traveling to a high altitude. It generally appears in patients who have acute mountain sickness and involves disorientation, lethargy, and nausea among other symptoms.
Of this group surveyed, 62% identified proper post concussion management and this lack of proper post concussion management could lead to SIS. [ 43 ] Both direct blows to the head and blows to the body can produce subdural hematomas, diffuse cerebral edema, subarachnoid hemorrhage, and ischemic stroke, all pathologies that can lead to death. [ 40 ]
[9] [3] In some cases, people will develop concomitant neurological features such as poor coordination, altered consciousness, or cerebral edema (High-altitude cerebral edema). [9] [3] On physical exam, increased breathing rates, increased heart rates, and a low-grade fever 38.5 o C (101.3 o F) are common.
Fluid replacement or fluid resuscitation is the medical practice of replenishing bodily fluid lost through sweating, bleeding, fluid shifts or other pathologic processes. . Fluids can be replaced with oral rehydration therapy (drinking), intravenous therapy, rectally such as with a Murphy drip, or by hypodermoclysis, the direct injection of fluid into the subcutaneous tis
PALERMO — One of the two kindergarteners injured in a Northern California school shooting in early December may not regain the use of his legs, the family told CBS Sacramento on Thursday.
ARIA-E refers to cerebral edema, involving the breakdown of the tight endothelial junctions of the blood-brain barrier and subsequent accumulation of fluid. [3] In a double-blind trial of the humanised monoclonal antibody solanezumab (n = 2042), sixteen patients (11 taking the drug, 5 taking a placebo), or 0.78% developed ARIA-E.