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  2. Hypokinesia - Wikipedia

    en.wikipedia.org/wiki/Hypokinesia

    Leadpipe rigidity is sustained resistance to passive movement throughout the whole range of motion, with no fluctuations. Cogwheel rigidity is jerky resistance to passive movement as muscles tense and relax. Spasticity, a special form of rigidity, is present only at the start of passive movement. It is rate-dependent and only elicited upon a ...

  3. Waddell's signs - Wikipedia

    en.wikipedia.org/wiki/Waddell's_signs

    With the possible exception of cogwheel rigidity, these are best understood as neuroanatomical maladaptations to long-continued pain and, as Waddell and colleagues have stressed, do not indicate faking or malingering but rather that there are psychosocial issues that militate against successfully treating low back pain by lumbar discectomy, and ...

  4. Signs and symptoms of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    When limbs of the person with PD are passively moved by others, a "cogwheel rigidity" is commonly seen. [1] Cogwheel-like or ratchety jerks are characterized by the articulation moving as opposed to the normal fluid movement; when a muscle is externally tried to move, it resists at first, but with enough force, it is partially moved until it ...

  5. Parkinsonism - Wikipedia

    en.wikipedia.org/wiki/Parkinsonism

    Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1] [2] Both hypokinetic (bradykinesia and akinesia) as well as hyperkinetic (cogwheel rigidity and tremors at rest) features are displayed by Parkinsonism. [3]

  6. Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Parkinson's_disease

    No cure for Parkinson's is known, and treatment focuses on alleviating symptoms. Initial treatment typically includes L-DOPA, MAO-B inhibitors, or dopamine agonists. As the disease progresses, these medications become less effective and may cause involuntary muscle movements. Diet and rehabilitation therapies can help improve symptoms.

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  9. Amantadine - Wikipedia

    en.wikipedia.org/wiki/Amantadine

    Amantadine was initially developed to prevent replication of the influenza A virus. [18] Its main clinical use today is treatment of Parkinson's disease. [18] Other uses include treatment of drug-induced extrapyramidal side effects, motor fluctuations during levodopa therapy in Parkinson's disease, traumatic brain injury, and autistic spectrum disorders.