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Zoledronic acid, also known as zoledronate and sold under the brand name Zometa among others, [7] by Novartis among others, is a medication used to treat a number of bone diseases. [3] These include osteoporosis , high blood calcium due to cancer , bone breakdown due to cancer, Paget's disease of bone [ 3 ] and Duchenne muscular dystrophy (DMD).
In large studies, women taking bisphosphonates for osteoporosis have had unusual fractures ("bisphosphonate fractures") in the femur (thigh bone) in the shaft (diaphysis or sub-trochanteric region) of the bone, rather than at the femoral neck, which is the most common site of fracture. However, these fractures are rare (12 in 14,195 women ...
They are used for the treatment of osteoporosis and other bone disorders that cause bone fragility and diseases where bone resorption is excessive. Osteoporosis is common in post-menopausal women and patients in corticosteroid treatment where biphosphonates have been proven a valuable treatment and also used successfully against Paget's disease ...
every month q.n. every night QNS q.n.s. quantity not sufficient q.o.d. every other day (from Latin quaque altera die) (deprecated; use "every other day" instead. See the do-not-use list) QOF: Quality and Outcomes Framework (system for payment of GPs in the UK National Health Service) q.o.h. every other hour q.s. as much as suffices (from Latin ...
The US National Osteoporosis Foundation recommends pharmacologic treatment for patients with hip or spine fracture thought to be related to osteoporosis, those with BMD 2.5 SD or more below the young normal mean (T-score -2.5 or below), and those with BMD between 1 and 2.5 SD below normal mean whose 10-year risk, using FRAX, for hip fracture is ...
Intraosseous infusion (IO) is the process of injecting medication, fluids, or blood products directly into the bone marrow; [1] this provides a non-collapsible entry point into the systemic venous system. [2] The intraosseous infusion technique is used to provide fluids and medication when intravenous access is not