Search results
Results From The WOW.Com Content Network
The troponin complex is responsible for coupling the sarcomere contraction cycle to variations in intracellular calcium concentration. Increased troponin T levels after an episode of chest pain indicates myocardial infarction. [7] It was discovered by the German physician Hugo A. Katus at the University of Heidelberg.
Test Sensitivity and specificity Approximate peak Description Troponin test: The most sensitive and specific test for myocardial damage. Because it has increased specificity compared with CK-MB, troponin is composed of 3 proteins- Troponin C, Cardic troponin I, and Cardiac troponin T. Troponin I especially has a high affinity for myocardial injury.
Elevated troponin levels are prognostically important in many of the conditions in which they are used for diagnosis. [ 36 ] In a community-based cohort study indicating the importance of silent cardiac damage, troponin I has been shown to predict mortality and first coronary heart disease event in men free from cardiovascular disease at ...
Cardiac arrests are fundamentally treated with CPR which includes chest compressions. These compressions serve two goals. First, the compressions circulate blood to the brain and other tissues which helps reduce their ischemia and attenuates later post-cardiac arrest syndrome. This goal is accomplished during the compression phase of the CPR ...
A blunt cardiac injury is an injury to the heart as the result of blunt trauma, typically to the anterior chest wall.It can result in a variety of specific injuries to the heart, the most common of which is a myocardial contusion, which is a term for a bruise (contusion) to the heart after an injury. [1]
After defibrillation, chest compressions should be continued for two minutes before another rhythm check. [30] This is based on a compression rate of 100-120 compressions per minute, a compression depth of 5–6 centimeters into the chest, full chest recoil, and a ventilation rate of 10 breath ventilations per minute. [ 30 ]
A complete blood count may show an elevated white count and a serum C-reactive protein may be elevated. Acute pericarditis is associated with a modest increase in serum creatine kinase MB (CK-MB). [ 5 ] and cardiac troponin I (cTnI), [ 6 ] [ 7 ] both of which are also markers for injury to the muscular layer of the heart.
Troponin I is a biomarker that responds to treatment interventions. Reductions in troponin I levels proved to reduce the risk of future CVD. [23] [24] [25] High sensitive troponin I used as a screening tool to assess a person's cardiovascular risk and has the potential to reduce the growing cost burden of the healthcare system. [26]