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Pinworm is the most common worm infection in the U.S., and up to half of kids can become infected at some time, according to the Centers for Disease Control and Prevention. We are the only hosts ...
Pinworm infections commonly occur in all parts of the world. [1] [5] They are the most common type of worm infection in Western Europe, Northern Europe and the United States. [5] School-aged children are the most commonly infected. [1] In the United States about 20% of children will develop pinworm at some point. [3]
The estimations of the number of eggs in a gravid female pinworm range from about 11,000 [19] to 16,000. [21] The egg-laying process begins about five weeks after initial ingestion of pinworm eggs by the human host. [19] The gravid female pinworms migrate through the colon towards the rectum at a rate of 12 to 14 cm per hour. [19]
Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations, including roundworm, hookworm, whipworm, threadworm (pinworm), and the intestinal form of trichinosis prior to its spread into the tissues beyond the digestive tract.
Pyrvinium (Viprynium) is an anthelmintic effective for pinworms. [1] Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. [2] [3] Pyrvinium was identified as a potent Wnt inhibitor, acting through activation of Casein kinase CK1α. [4] [5]