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The Best ED Medication for Men: Pros & Cons of Top ED Pills. Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world.
Blood flow is often blamed when it comes to erectile dysfunction, but a new medical review suggests that treatment plans shouldn’t ignore what’s also happening psychologically.
The term erectile dysfunction does not encompass other erection-related disorders, such as priapism. Treatment of ED encompasses addressing the underlying causes, lifestyle modification, and addressing psychosocial issues. [4] In many instances, medication-based therapies are used, specifically PDE5 inhibitors like sildenafil. [13]
Venous leak, also called venogenic erectile dysfunction and penile venous insufficiency, is one category of vascular-induced (vasculogenic) impotence – a cause of erectile dysfunction in males. [2] It affects all ages, being particularly awkward in young men. [ 3 ]
For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]
PDE5 inhibitors are contraindicated within 24 hours (or 48 hours with tadalafil) of taking alpha-blockers, soluble guanylate cyclase stimulators, or nitrate medications such as isosorbide mononitrate or isosorbide dinitrate. [1] Concurrent use of these medications can lead to life-threatening low blood pressure. [5]
Papaverine is used as an erectile dysfunction drug, alone or sometimes in combination. [6] [7] Papaverine, when injected in penile tissue, causes direct smooth muscle relaxation and consequent filling of the corpus cavernosum with blood resulting in erection. A topical gel is also available for ED treatment. [8]
Trimix is a combination of three drugs: alprostadil, papaverine, and phentolamine. These medications work in combination to increase blood flow to the penis, resulting in an erection. [ 1 ] [ 2 ] [ 3 ] Alprostadil is a prostaglandin vasodilator that allows more blood to flow into the area by relaxing the smooth muscle in the blood vessels of ...
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