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Melatonin can lower follicle-stimulating hormone levels. [52] Melatonin's effects on human reproduction remain unclear. [53] Some supplemental melatonin users report an increase in vivid dreaming. Extremely high doses of melatonin increased REM sleep time and dream activity in people both with and without narcolepsy. [54]
Side effects from DHT blockers used in hair loss prevention shampoos are also uncommon. Some ingredients may cause irritation, dry skin, itchy skin or other similarly minor effects.
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
“Melatonin is most effective for helping sleep, but also helps with nighttime acid reflux, along with antioxidant, immune, and neuroprotective benefits,” he says.
A common example of an indolamine is the tryptophan derivative serotonin, a neurotransmitter involved in mood and sleep. [1] Another example of an indolamine is melatonin. In biochemistry, indolamines are substituted indole compounds that contain an amino group. Examples of indolamines include the lysergamides.
Pattern hair loss (also known as androgenetic alopecia (AGA) [1]) is a hair loss condition that primarily affects the top and front of the scalp. [ 2 ] [ 3 ] In male-pattern hair loss ( MPHL ), the hair loss typically presents itself as either a receding front hairline, loss of hair on the crown and vertex of the scalp, or a combination of both.