Search results
Results From The WOW.Com Content Network
Intrinsic factor is required for the absorption of vitamin B 12 in the diet. A long-term deficiency in vitamin B 12 can lead to megaloblastic anemia, characterized by large fragile red blood cells. Pernicious anaemia results from autoimmune destruction of gastric parietal cells, precluding the synthesis of intrinsic factor and, by extension ...
Intrinsic factor (IF), cobalamin binding intrinsic factor, [5] also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells (in humans) or chief cells (in rodents) of the stomach. It is necessary for the absorption of vitamin B 12 later on in the distal ileum of the small intestine. [6]
The same cells in the stomach that produce gastric hydrochloric acid, the parietal cells, also produce a molecule called the intrinsic factor (IF), which binds the B 12 after its release from haptocorrin by digestion, and without which only 1% of vitamin B 12 is absorbed. Intrinsic factor (IF) is a glycoprotein, with a molecular weight of 45 kDa.
Lack of intrinsic factor: intrinsic factor is a protein produced by parietal cells in the stomach, and needed in the ileum for the absorption of vitamin B 12. Lack of intrinsic factor is most commonly due to an autoimmune attack on the cells that create it in the stomach, and this condition takes the name "pernicious anemia".
Parietal cells, stomach epithelium cells that secrete gastric acid and intrinsic factor to aid in digestion. The parietal bone . Topics referred to by the same term
Receptors bind to the vitamin B12-gastric intrinsic factor complex and are taken into the cell. Resorption of unconjugated bile salts. Bile that was released and not used in emulsification of lipids are reabsorbed in the ileum. Also known as the enterohepatic circulation. Secretion of immunoglobulins.
Intrinsic factor, a glycoprotein produced by the parietal cells of the stomach, which is necessary for the absorption of vitamin B 12 Topics referred to by the same term This disambiguation page lists articles associated with the title Castle factors .
With this simple geometrical similarity, based on the laws of optics, the eye functions as a transducer, as does a CCD camera. In the visual system, retinal , technically called retinene 1 or "retinaldehyde", is a light-sensitive molecule found in the rods and cones of the retina .