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Aliskiren (brand names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors. It is used for essential (primary) hypertension . [ 2 ] While used for high blood pressure, other better studied medications are typically recommended due to concerns of higher side effects and less evidence of benefit.
[1] [2] It contains aliskiren, a renin inhibitor; amlodipine, as the besylate, a calcium channel blocker; and hydrochlorothiazide, a thiazide diuretic. [1] It is taken by mouth . [ 1 ]
Considerations include factors such as age, race, and other medical conditions. [47] In the United States, JNC8 (2014) recommends any drug from one of the four following classes to be a good choice as either initial therapy or as an add-on treatment: thiazide -type diuretics, calcium channel blockers , ACEis, or ARBs.
Aliskiren/hydrochlorothiazide, sold under the brand name Tekturna HCT among others, is a fixed-dose combination medication for the treatment of hypertension ...
Aliskiren, the third-generation renin inhibitor. Aliskiren, an orally active non-peptide renin inhibitor, was the first drug in its class on the market. It is used to treat hypertension as monotherapy or in combination with other antihypertensive agents. [7] [39] The key to the discovery of aliskiren was crystallography and molecular modeling ...
Gerontological nursing is complex and requires extensive interventions to keep the elderly safe. Nurses must be able to accommodate their patients for the vision loss, hearing loss, and dental issues. Elderly people with poor vision can be given reading materials with larger font, be provided with magnifying glasses, and brighter lighting. [15]
The drug combination aliskiren/amlodipine (INNs, trade names Tekamlo and Rasilamlo) is an antihypertensive. Clinical trials have shown it to be more effective than amlodipine on its own, [ 1 ] with a high dosing regime (aliskiren 300 mg/amlodipine 10 mg) being more effective than olmesartan/amlodipine with comparable tolerability.
Website: www.nicheprogram.org. Nurses Improving Care for Healthsystem Elders (NICHE) is a program of the Hartford Institute for Geriatric Nursing at New York University College of Nursing, that works to achieve systematic nursing change to benefit hospitalized older patients.