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Subsequent investigation led to a report by Andrew Conway Ivy, who testified that the research was "an example of human experiments which were ideal because of their conformity with the highest ethical standards of human experimentation". [189] The trials contributed to the formation of the Nuremberg Code in an effort to prevent such abuses. [190]
Animal testing is widely used to aid in research of human disease when human experimentation would be unfeasible or unethical. [26] This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution. [27]
An animal model (short for animal disease model) is a living, non-human, often genetic-engineered animal used during the research and investigation of human disease, for the purpose of better understanding the disease process without the risk of harming a human. Although biological activity in an animal model does not ensure an effect in humans ...
Disease models are divided into three categories: homologous animals have the same causes, symptoms and treatment options as would humans who have the same disease, isomorphic animals share the same symptoms and treatments, and predictive models are similar to a particular human disease in only a couple of aspects, but are useful in isolating ...
Illnesses transmitted from animals to humans could kill 12 times as many people in 2050 than they did in 2020, researchers have warned.. Epidemics caused by zoonotic diseases – also known as ...
Unethical human experimentation is human experimentation that violates the principles of medical ethics. Such practices have included denying patients the right to informed consent , using pseudoscientific frameworks such as race science , and torturing people under the guise of research.
In infectious disease research, China invests more than the U.S. does in conducting research on non-human primates. "Select agents and toxins" refers to a list of over 60 substances that pose the greatest risk to public health, and China uses non-human primates to test treatment of these select agents and toxins more than the U.S. does. [117]
In 1954, the Universities Federation for Animal Welfare (UFAW) decided to sponsor systematic research on the progress of humane techniques in the laboratory. [2] In October of that year, William Russell, described as a brilliant young zoologist who happened to be also a psychologist and a classical scholar, and Rex Burch, a microbiologist, were appointed to inaugurate a systematic study of ...