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Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.
We asked doctors whether or not MS is hereditary, and they discussed genetic, as well as environmental, factors that could result in a person developing multiple sclerosis.
Currently it is unknown what the primary cause of MS is; if MS is a heterogeneous disease, the lesion development process would not be unique. In particular, some PPMS patients having a special clinical course named rapidly progressive multiple sclerosis could have a special genetic cause [ 47 ] and a different development process.
Heredity, also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic information of their parents.
In genetics, a maternal effect occurs when the phenotype of an organism is determined by the genotype of its mother. [1] For example, if a mutation is maternal effect recessive, then a female homozygous for the mutation may appear phenotypically normal, however her offspring will show the mutant phenotype, even if they are heterozygous for the mutation.
Having grandparents who’ve had certain types of cancer can influence your own risk of developing the disease, Carolyn Haskins, licensed genetic counselor at Moffitt Cancer Center, tells Yahoo Life.
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