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Estrogen conjugates are conjugated at the C3, C16α, and/or C17β positions, where hydroxyl groups are available. [1]Estrogen conjugates have been used as pharmaceutical estrogens, as in estrone sulfate as estropipate (piperazine estrone sulfate) and in conjugated estrogens (Premarin) and conjugated estriol (Progynon, Emmenin).
Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications. [11] [7] [1] [12] It is a mixture of the sodium salts of estrogen conjugates found in horses, such as estrone sulfate and ...
Esterified estrogens (EEs), sold under the brand names Estratab and Menest among others, is an estrogen medication which is used hormone therapy for menopausal symptoms and low sex hormone levels in women, to treat breast cancer in both women and men, and to treat prostate cancer in men.
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Synthetic conjugated estrogens (Cenestin, Enjuvia) [1] – 0.3 mg, 0.45 mg, 0.625 mg, 0.9 mg, 1.25 mg; Atypical (dual estrogen and nitrogen mustard alkylating antineoplastic): Estramustine phosphate sodium (Emcyt) – 140 mg
Estrogens are synthesized in all vertebrates [4] and some insects. [5] Quantitatively, estrogens circulate at lower levels than androgens in both men and women. [6] While estrogen levels are significantly lower in males than in females, estrogens nevertheless have important physiological roles in males. [7]
Those taking conjugated equine estrogens plus medroxyprogesterone acetate saw a 7% increase in HDL-C measures. So-called bad cholesterol — low-density lipoprotein cholesterol (LDL-C ...
During the reproductive years of human females, levels of estradiol are somewhat higher than that of estrone, except during the early follicular phase of the menstrual cycle; thus, estradiol may be considered the predominant estrogen during human female reproductive years in terms of absolute serum levels and estrogenic activity.