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Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye.
Common side effects include nausea and loss of appetite. [6] Other side effects include liver inflammation, methemoglobinemia, [7] and a number of types of skin rashes. [4] While the safety of use during pregnancy is not entirely clear some physicians recommend that it be continued in those with leprosy. [4] It is of the sulfone class. [4]
Eye, ear or bladder infections; usually applied directly to the eye or inhaled into the lungs; rarely given by injection, although the use of intravenous colistin is experiencing a resurgence due to the emergence of multi drug resistant organisms. Kidney and nerve damage (when given by injection)
Daptomycin, sold under the brand name Cubicin among others, is a lipopeptide antibiotic used in the treatment of systemic and life-threatening infections caused by Gram-positive organisms. [4] Daptomycin was removed from the World Health Organization's List of Essential Medicines in 2019.
••Snellen's near chart (1/17th reduction of distant chart)-do-; standard chart of alphabets; video link •Colour vision: to test colour vision ••Ishihara's chart: to determine the type of colour blindness Stenopaeic slit: detection of axis of the cylindrical (astigmatism) power of the eye; glaucoma testing Implants - •Intraocular lens
Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [ 3 ] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides.Significant glycopeptide antibiotics include the anti-infective antibiotics vancomycin, teicoplanin, telavancin, ramoplanin, avoparcin and decaplanin, corbomycin, complestatin and the antitumor antibiotic bleomycin.
The FDA requires nonclinical laboratory studies on new drugs, food additives, and chemicals to assess their safety and potential effectiveness in humans in compliance with 21 CFR Part 58, Good Laboratory Practice for Nonclinical Studies under the Federal Food Drug and Cosmetic Act and Public Health Service Act. [16]