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Trazodone lacks any affinity for the muscarinic acetylcholine receptors, so does not produce anticholinergic side effects. mCPP, a non-selective serotonin receptor modulator and serotonin releasing agent , is an active metabolite of trazodone and has been suggested to possibly play a role in its therapeutic benefits.
This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence. [1] [2] [3] Very common.
Mirtazapine is reported to have fewer sexual side effects, most likely because it antagonizes 5-HT 2 and 5-HT 3 receptors and may, in some cases, reverse sexual dysfunction induced by SSRIs by the same mechanism. [164] Bupropion, a weak NDRI and nicotinic antagonist, may be useful in treating reduced libido as a result of SSRI treatment. [165]
Please review the contents of the article and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed . Find sources: "Serotonin antagonist and reuptake inhibitor" – news · newspapers · books · scholar · JSTOR ( September 2015 )
A builder who committed the "bloodthirsty" murder of a 38-year-old woman and then dismembered her body has been jailed for the rest of his life.
In addition, due to their blockade of certain serotonin receptors, serotonergic neurotransmission is not facilitated in unwanted areas, which prevents the incidence of many side effects often associated with selective serotonin reuptake inhibitor (SSRI) antidepressants; [1] [3] hence, in part, the "specific serotonergic" label of NaSSAs. [2]