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This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence. [1] [2] [3] Very common.
Trazodone lacks any affinity for the muscarinic acetylcholine receptors, so does not produce anticholinergic side effects. mCPP, a non-selective serotonin receptor modulator and serotonin releasing agent , is an active metabolite of trazodone and has been suggested to possibly play a role in its therapeutic benefits.
Please review the contents of the article and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed . Find sources: "Serotonin antagonist and reuptake inhibitor" – news · newspapers · books · scholar · JSTOR ( September 2015 )
Antidepressants could increase the risk of suicidal thoughts and behavior in people with depression under the age of 25. In 2004, the U.S. Food and Drug Administration along with the Neuro-Psychopharmacologic Advisory Committee and the Anti-Infective Drugs Advisory Committee, concluded that there was a causal link between newer antidepressants and pediatric suicidality. [7]
The review concluded on the basis of daridorexant's small effect size that it did not show an overall material benefit in the treatment of insomnia. [19] Conversely, it concluded that lemborexant—as well as the Z-drug eszopiclone —had the best profiles overall in terms of efficacy , tolerability , and acceptability among all of the assessed ...
A number of non-SSRI drugs are not associated with sexual side effects (such as bupropion, mirtazapine, tianeptine, agomelatine, tranylcypromine, and moclobemide [57] [58] [59]). Several studies have suggested that SSRIs may adversely affect semen quality. [60] [61]