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  2. Antiphospholipid syndrome - Wikipedia

    en.wikipedia.org/wiki/Antiphospholipid_syndrome

    Antiphospholipid syndrome is known for causing arterial or venous blood clots, in any organ system, and pregnancy-related complications.While blood clots and pregnancy complications are the most common and diagnostic symptoms associated with APS, other organs and body parts may be affected like platelet levels, heart, kidneys, brain, and skin.

  3. Lupus and pregnancy - Wikipedia

    en.wikipedia.org/wiki/Lupus_and_pregnancy

    Pregnancy outcome appears to be worse in those with lupus whose disease flares up during pregnancy. [7] Miscarriages in the first trimester appear either to have no known cause or to be associated with signs of active lupus. [8] Later losses appear to occur primarily due to the antiphospholipid syndrome, in spite of treatment with heparin and ...

  4. Catastrophic antiphospholipid syndrome - Wikipedia

    en.wikipedia.org/wiki/Catastrophic...

    Catastrophic antiphospholipid syndrome (CAPS), also known as Asherson's syndrome, is a rare autoimmune disease in which widespread, intravascular clotting causes multi-organ failure. [1] The syndrome is caused by antiphospholipid antibodies that target a group of proteins in the body that are associated with phospholipids .

  5. Lupus anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Lupus_anticoagulant

    In a suspected antiphospholipid syndrome, lupus anticoagulant is generally tested in conjunction with anti-apolipoprotein antibodies and anti-cardiolipin antibodies, and diagnostic criteria require one clinical event (i.e. thrombosis or pregnancy complication) and two positive blood test results spaced at least three months apart that detect at ...

  6. Reproductive immunology - Wikipedia

    en.wikipedia.org/wiki/Reproductive_immunology

    An increase in the prevalence of antiphospholipid antibodies (known as antiphospholipid syndrome) can be found in many recurrent miscarriage patients. However, there is no evidence that the increase in antiphospholipid antibodies harms the pregnancy, but is thought to be indicative of immune dysfunction and proinflammatory responses in regards ...

  7. Hypercoagulability in pregnancy - Wikipedia

    en.wikipedia.org/.../Hypercoagulability_in_pregnancy

    Among other causes of hypercoagulability, Antiphospholipid syndrome has been associated with adverse pregnancy outcomes including recurrent miscarriage. [8] Deep vein thrombosis has an incidence of one in 1,000 to 2,000 pregnancies in the United States, [2] and is the second most common cause of maternal death in developed countries after ...

  8. Protein S deficiency - Wikipedia

    en.wikipedia.org/wiki/Protein_S_deficiency

    Human Chr 3. In terms of the cause of protein S deficiency it can be in inherited via autosomal dominance.A mutation in the PROS1 gene triggers the condition. The cytogenetic location of the gene in question is chromosome 3, specifically 3q11.1 [6] [7] Protein S deficiency can also be acquired due to vitamin K deficiency, treatment with warfarin, liver disease, kidney disease, chemotherapy ...

  9. Recurrent miscarriage - Wikipedia

    en.wikipedia.org/wiki/Recurrent_miscarriage

    Antiphospholipid syndrome: The antiphospholipid syndrome is an autoimmune disease that is a common cause of recurrent pregnancy loss. [34] [15] Around 15% of the women who have recurrent miscarriages have high levels of antiphospholipid antibodies. [34]