Ads
related to: waldenstrom s disease symptoms and treatment- WM Efficacy Data
Find Data From A
Waldenstrom's Clinical Trial
- Educational Materials
Find A Selection Of Resources
Help Your Patients With WM
- Reimbursement Resources
Find Reimbursement Resources
Specialty Pharmacy
- WM Dosing Guidelines
Get Dosing & Prescribing Info
For A WM Treatment
- Mechanism Of Action
Learn More About A Treatment
Option Of Waldenstrom’s
- Patient Support Program
Offers Information & Resources Your
Patients May Need During Treatment.
- WM Efficacy Data
careinfo.mayoclinic.org has been visited by 100K+ users in the past month
Search results
Results From The WOW.Com Content Network
Symptoms including blurring or loss of vision, headache, and (rarely) stroke or coma are due to the effects of the IgM paraprotein, which may cause autoimmune phenomena or cryoglobulinemia. Other symptoms of Waldenström macroglobulinemia are due to hyperviscosity syndrome, which is present in 6–20% of patients.
Bing–Neel syndrome (BNS) is an extremely rare neurologic complication of Waldenström macroglobulinemia (WM), which is a chronic lymphoproliferative disorder. [1] There's no clear definition of BNS but what is known so far is that unlike WM, It involves the central nervous system (CNS), infiltrated by differentiated malignant B cells and by having hyperglobulinemia. [2]
The condition was first described in 1909 by Danish ophthalmologist Christian Frederick Heerfordt, for whom the syndrome is now named. [6] It was originally attributed to mumps, but after further studies by Swedish doctor Jan G. Waldenström in 1937, it was classified as a distinct manifestation of sarcoidosis.
According to Macmillan Cancer Support, Waldenström’s macroglobulinaemia is a type of non-Hodgkin lymphoma, which is sometimes called lymphoplasmacytic lymphoma.
While this disease is commonly referred to as cryoglobulinemia in the medical literature, it is better termed cryoglobulinemic disease for two reasons: 1) cryoglobulinemia is also used to indicate the circulation of (usually low levels of) cryoglobulins in the absence of any symptoms or disease and 2) healthy individuals can develop transient ...
Treatment is highly individualized and depends on a range of factors, including the subtype of the disease, its stage, the patient's age, and other medical conditions. [ 17 ] Patients with early-stage indolent lymphoma may be cured with radiation therapy , but most patients have widespread disease at the time of diagnosis.
Waldenström first described, in 1944, patients with a disease that has subsequently been named for him, Waldenström's macroglobulinemia, a "hyperviscosity syndrome" in which symptoms are caused by abnormal lymphocytes that prevent normal bone marrow function, which causes anemia and hepatosplenomegaly, and secrete large immunoglobulins ...
In rare cases, patients may have minimal or no symptoms at presentation or after successful treatment of their disorder. These patients may be monitored every 2–3 months for symptoms and disease progression. Otherwise, treatment is divided based on the local versus systemic spread of its clonal plasma cells.
Ad
related to: waldenstrom s disease symptoms and treatment