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Intrahepatic cholestasis of pregnancy (ICP), also known as obstetric cholestasis, cholestasis of pregnancy, jaundice of pregnancy, and prurigo gravidarum, [1] is a medical condition in which cholestasis occurs during pregnancy. [2] It typically presents with itching and can lead to complications for both mother and fetus. [2]
Neonatal cholestasis can present in newborn infants within the first few months of life. [1] The incidence of neonatal cholestasis is approximately 1 in 2,500 term births. [5] While neonatal cholestasis can present from a number of pathologic causes, 35-40% of neonatal cholestasis cases are caused by biliary atresia. [3]
This causes an accumulation of bilirubin in the blood (hyperbilirubinemia), leading to the symptoms of jaundice. [ citation needed ] If the neonatal jaundice is not resolved with simple phototherapy , other causes such as biliary atresia , Progressive familial intrahepatic cholestasis , bile duct paucity, Alagille syndrome , alpha 1-antitrypsin ...
Intrahepatic cholestasis of pregnancy (ICP) is an acute cause of cholestasis that manifests most commonly in the third trimester of pregnancy. [15] It affects 0.5–1.5% of pregnancies in Europe and the US and up to 28% in women of Mapuche ethnicity in Chile. [60]
Any treatment for neonatal jaundice "must occur within the first 10 days of life, else [the condition] could cause permanent brain damage and severe cerebral palsy", says Prof Ezeaka.
This is a list of conditions that can cause posthepatic jaundice: Choledocholithiasis (common bile duct gallstones). It is the most common cause of obstructive jaundice. Pancreatic cancer of the pancreatic head; Biliary tract strictures; Biliary atresia; Primary biliary cholangitis; Cholestasis of pregnancy; Acute Pancreatitis; Chronic Pancreatitis
A Michigan couple’s newborn daughter died after they ignored a midwife’s warning that the baby’s jaundice could lead to brain damage or death. Baby dies after parents refuse treatment for ...
The underappreciated link between these mundane activities is good balance, which geriatricians say is key to maintaining an independent lifestyle as we age. Lacking balance can be dangerous. In ...