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Decongestants are often used in conjunction with cold medications or to combat pregnancy rhinitis in pregnant women. Common decongestants include pseudoephedrine and phenylephrine . [ 14 ] Pseudoephedrine is an alpha-adrenergic receptor agonist that enacts a vasoconstrictive effect to reduce airflow resistance in the nasal cavity and allow ...
[4] [5] Use is not recommended during pregnancy. [2] Xylometazoline is in the decongestant and alpha-adrenergic agonist families of medication. [5] [6] One study classified it with selectivity ratios in alpha 2 adrenergic receptors of 151 for a2A vs a2B, 4.5 a2A vs a2C, and 33.9 a2B vs a2C. Making it a highly selective a2A agonist. [7]
Propylhexedrine, sold under the brand name Benzedrex among others, is an alkylamine primarily utilized as a topical nasal decongestant. [1] Its main indications are relief of congestion due to colds, allergies, and allergic rhinitis. [2]
Over the counter expectorants (like Mucinex) or a decongestant (like Sudafed) can help with your chest congestion, says Dr. Watkins. Decongestants and expectorants are both effective at treating ...
After an FDA advisory committee said the decongestant phenylephrine, an ingredient found in many oral cold and flu medications, is ineffective, experts weigh in on alternatives.
Decongestants are available in oral and intranasal forms. Naphazoline and oxymetazoline are common topical (intranasal) decongestants, whilst pseudoephedrine is the most common example of oral decongestant used to reduce nasal congestion. Topical decongestants have a faster onset of action compared with oral ones. [12] Side effects