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Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
Animals, including humans, can convert cyanocobalamin to any one of the active vitamin B 12 compounds. [21] Cyanocobalamin is one of the most widely manufactured vitamers in the vitamin B 12 family (the family of chemicals that function as B 12 when put into the body), because cyanocobalamin is the most air-stable of the B 12 forms. [22]
Cyanocobalamin (Artificial B12) Index of chemical compounds with the same molecular formula This set index page lists chemical structure articles associated with the same molecular formula .
Injection of hydroxycobalamin is often used if digestive absorption is impaired, [2] but this course of action may not be necessary with high-dose oral supplements (such as 0.5–1.0 mg or more), [94] [95] because with large quantities of the vitamin taken orally, even the 1% to 5% of free crystalline B 12 that is absorbed along the entire ...
Drugs come with a recommended dose in milligrams or micrograms per kilogram of body weight, and that is used in conjunction with the patient's age and body weight to determine a safe dose. In single-dose scenarios, the patient's body weight and the drug's recommended dose per kilogram are used to determine a safe one-time dose.
The term dosage form may also sometimes refer only to the pharmaceutical formulation of a drug product's constituent substances, without considering its final configuration as a consumable product (e.g., capsule, patch, etc.). Due to the somewhat ambiguous nature and overlap of these terms within the pharmaceutical industry, caution is ...
Weight gain will occur when an animal is in a positive energy balance, meaning energy provided as calories in the diet exceed calories expended. [10] Evidence suggests that middle-aged cats and dogs, especially those between the ages of 5 and 10, may be at an increased risk of obesity. [11]
Vitamin B 12 deficiency; Other names: Hypocobalaminemia, cobalamin deficiency: Image of the cervical spinal cord in vitamin B 12 deficiency showing subacute combined degeneration. . (A) The midsagittal T2 weighted image shows linear hyperintensity in the posterior portion of the cervical tract of the spinal cord (black arrow