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Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in ...
The test can detect antipsychotic-like activity both in the case of dopamine D 2 receptor antagonists and in the case of drugs lacking D 2 receptor antagonism. [1] [2] [6] The occupancy of the D 2 receptor by antagonists of this receptor required to inhibit the CAR is around 65 to 80%, which is similar to the occupancy at which therapeutic antipsychotic effects occur in humans with these drugs.
The directive stresses the use of the 3R principle (replacement, refinement, reduction) and animal welfare when conducting animal testing on non-human primates. [21] A 2013 amendment to the German Animal Welfare Act, with special regulations for monkeys, resulted in a near total ban on the use of great apes as laboratory animals. [22]
An Essay on Humanity to Animals is a 1798 book by English theologian Thomas Young. It advocates for the ethical treatment and welfare of animals. It argues for recognizing animals' natural rights and condemns the various forms of cruelty inflicted upon them in human activities. Drawing on moral, scriptural, and philosophical reasoning, Young ...
Transgenic animal production consists of injecting each construct into 300–350 eggs, typically representing three days' work. Twenty to fifty mice will normally be born from this number of injected eggs. These animals are screened for the presence of the transgene by a polymerase chain reaction genotyping assay. The number of transgenic ...
In 1954, the Universities Federation for Animal Welfare (UFAW) decided to sponsor systematic research on the progress of humane techniques in the laboratory. [2] In October of that year, William Russell, described as a brilliant young zoologist who happened to be also a psychologist and a classical scholar, and Rex Burch, a microbiologist, were appointed to inaugurate a systematic study of ...
Articles related to animal testing, the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study. Experimental research with animals is usually conducted in universities, medical schools, pharmaceutical companies, defense establishments, and commercial facilities that ...
Doctors Against Animal Experiments (DAAE; Ärzte gegen Tierversuche) is an animal rights organization based in Cologne, which campaigns for the complete abolition of animal testing under the motto "Medical progress is important - animal testing is the wrong way".