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Pleomorphic adenoma (or benign mixed tumor) is a common benign salivary gland neoplasm characterised by neoplastic proliferation of epithelial (ductal) cells along with myoepithelial components, having a malignant potentiality.
Adenomas are benign tumors of gland-forming cells, and are usually specified further by their cell or organ of origin, as in hepatic adenoma (a benign tumor of hepatocytes, or liver cells). Teratomas contain many cell types such as skin, nerve, brain and thyroid, among others, because they are derived from germ cells. [36]
In approximately 75% of cases ca ex PAs arise in a pleomorphic adenoma that is apparent when the tumour is excised. [2] In the other approximately 25% of cases the individual had a pleomorphic adenoma excised previously and the diagnosis is made based on (1) the presence of a carcinoma, and (2) the history of a pleomorphic adenoma at that location.
Benign tumour of the submandibular gland, also known as pleomorphic adenoma, presented as a painless neck mass in a 40-year-old man. At the left of the image is the white tumour with its characteristic cartilaginous cut surface. To the right is the normally lobated submandibular salivary gland. Warthin's tumor; Myoepithelioma; Basal cell ...
An adenoma is a benign tumor ... they have the potential to cause serious health ... Warthin tumors, and benign mixed tumors (also known as pleomorphic adenomas ...
Pleomorphic lipomas, like spindle-cell lipomas, occur for the most part on the backs and necks of elderly men and are characterized by floret giant cells with overlapping nuclei. [7]: 625 Spindle-cell lipomas are asymptomatic, slow-growing, subcutaneous tumors that have a predilection for the posterior back, neck, and shoulders of older men.
Imiquimod (Aldara) has been used with success for squamous-cell carcinoma in situ of the skin and the penis, but the morbidity and discomfort of the treatment is severe. An advantage is the cosmetic result: after treatment, the skin resembles normal skin without the usual scarring and morbidity associated with standard excision.
Sarcomatoid carcinoma is a type of rare lung tumour under the category of poorly differentiated Non-small-cell lung carcinoma (NSCLC). Based on its histological characteristics, it can be classified into giant cell carcinoma (almost completely consists of giant cells), spindle cell carcinoma (almost completely consists of spindle cells), pleomorphic carcinoma (at least 10% spindle/giant cells ...