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The corneal limbus is the border between the cornea and the sclera. [1] It is highly vascularised. [1] Its stratified squamous epithelium is continuous with the epithelium covering the cornea. [2] The corneal limbus contains radially-oriented fibrovascular ridges known as the palisades of Vogt that contain limbal stem cells.
Damage to the limbus can lead to limbal stem cell deficiency (LSCD); this may be primary - related to an insufficient stromal microenvironment to support stem cell functions, such as aniridia, and other congenital conditions, or secondary – caused by external factors that destroy the limbal stem cells, such as chemical or thermal burns, radiation, surgery, infection, use of contact lenses ...
Cornea, 9. Trabecular meshwork and Schlemm's canal. 10. Corneal limbus and 11. Sclera; 12. Conjunctiva, 13. Uvea with 14. Iris, 15. Ciliary body. The anterior segment or anterior cavity [1] is the front third of the eye that includes the structures in front of the vitreous humour: the cornea, iris, ciliary body, and lens. [2] [3]
Diagram of a human eye (horizontal section of the right eye) 1. Lens, 2. Zonule of Zinn or Ciliary zonule, 3. Posterior chamber and 4. Anterior chamber with 5. Aqueous humour flow; 6. Pupil, 7. Corneosclera or Fibrous tunic with 8. Cornea, 9. Trabecular meshwork and Schlemm's canal. 10. Corneal limbus and 11. Sclera; 12. Conjunctiva, 13. Uvea ...
The cornea is typically about 11.5 mm (0.45 in) in diameter, and 0.5 mm (500 μm) in thickness near its centre. The posterior chamber constitutes the remaining five-sixths; its diameter is typically about 24 mm (0.94 in). An area termed the limbus connects the cornea and sclera.
The function of the Bowman's layer remains unclear and it appears to have no critical function in corneal physiology. [3] Recently, it is postulated that the layer may act as a physical barrier to protect the subepithelial nerve plexus and thereby hastens epithelial innervation and sensory recovery.
A limbal ring is a dark ring around the iris of the eye, where the sclera meets the cornea. [1] It is a dark-colored manifestation of the corneal limbus resulting from optical properties of the region. [2] The appearance and visibility of the limbal ring can be negatively affected by a variety of medical conditions concerning the peripheral ...
The anterior chamber is the aqueous humor-filled space inside the eye between the iris and the cornea's innermost surface, the endothelium. [1] Hyphema, anterior uveitis and glaucoma are three main pathologies in this area. In hyphema, blood fills the anterior chamber as a result of a hemorrhage, most commonly after a blunt eye injury.