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Vitamin D2 vs. D3 Uses. Both vitamin D2 and vitamin D3 will help to increase vitamin D levels in the blood, says Pelitera. However, some studies have shown that supplementing vitamin D3 does a ...
In addition to calcitriol, other vitamin D metabolites may contribute to vitamin D's biological effects. For example, CYP11A1 , an enzyme chiefly known for its role in steroidogenesis , has been found to hydroxylate vitamin D3 at several positions, including C-20, C-22, and C-23, without cleaving the side chain.
Vitamin D3, aka cholecalciferol, is important for bone health and immune function. Experts discuss benefits, sources, risks and who needs a supplement. How to get the most out of vitamin D3
The body produces vitamin D3, which is converted into active vitamin D. Getting five to 30 minutes of UV exposure midday at least a few times a week is thought to be enough to maintain sufficient ...
[9] [10] Vitamin-D supplements may not be effective in people with severe kidney disease. [11] [10] Excessive doses in humans can result in vomiting, constipation, muscle weakness, and confusion. [5] Other risks include kidney stones. [11] Doses greater than 40 000 IU (1000 μg) per day are generally required before high blood calcium occurs. [12]
Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2), are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.