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Hippocampus anatomy describes the physical aspects and properties of the hippocampus, a neural structure in the medial temporal lobe of each cerebral hemisphere of the brain. It has a distinctive, curved shape that has been likened to the sea-horse creature of Greek mythology , and the ram's horns of Amun in Egyptian mythology .
The hippocampal subfields are four subfields CA1, CA2, CA3, and CA4 that make up the structure of the hippocampus.Regions described in the hippocampus are the head, body, and tail, and other hippocampal subfields include the dentate gyrus, the presubiculum, and the subiculum.
Schaffer collaterals are the axons of the neurons in the CA3 regions of the hippocampus that form synapses in the CA1 regions. The hippocampus is a part of the feedback process that sends signals to stop cortisol production. Thus, a damaged hippocampus can cause memory loss and inability of cognitive function.
The hippocampus (pl.: hippocampi; via Latin from Greek ἱππόκαμπος, 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus , and the subiculum are components of the hippocampal formation located in the limbic system .
A reconstruction of a pyramidal cell. Soma and dendrites are labeled in red, axon arbor in blue. (1) Soma, (2) Basal dendrite, (3) Apical dendrite, (4) Axon, (5) Collateral axon. One of the main structural features of the pyramidal neuron is the conic shaped soma, or cell body, after which the neuron is named.
[18] [19] Axons from the entorhinal cortex synapse primarily on the dendritic spines of outer layer dentate granule cells. [20] The entorhinal cortex passes sensory information from neocortical structures to the hippocampal formation. [19] The pathway allows sensory information to reach the hippocampus for encoding.
Association fibers are axons (nerve fibers) that connect cortical areas within the same cerebral hemisphere. [1]In human neuroanatomy, axons within the brain, can be categorized on the basis of their course and connections as association fibers, projection fibers, and commissural fibers. [1]
The axons of these neurons in the hippocampus terminate primarily in the stratum lucidum and stratum radiatum of CA3. Spiny neurons are of importance because of their "pivotal role in motor control, habit formation, and motivated behavior". They receive synaptic inputs from mossy fibers boutons, as well as multiple other synaptic terminals.