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The mediastinum has three main parts: the anterior mediastinum (front), the middle mediastinum, and the posterior mediastinum (back). Masses in the anterior portion of the mediastinum can include thymoma, lymphoma , pheochromocytoma , germ cell tumors including teratoma , thyroid tissue, and parathyroid lesions.
Pain can occur with mediastinitis but the location of the pain depends on which part of the mediastinum is involved. When the upper mediastinum is involved, the pain is typically retro-sternal pain. When the lower mediastinum is involved, pain can be located between in the scapulae and radiate around to the chest. [2]
Micrograph of a primary mediastinal large B-cell lymphoma, a cause of mediastinal lymphadenopathy. H&E stain. Mediastinal lymphadenopathy or mediastinal adenopathy is an enlargement of the mediastinal lymph nodes.
The diagnosis of a mediastinal germ cell tumor should be considered in all young males with a mediastinal mass. In addition to physical examination and routine laboratory studies, initial evaluation should include CT of the chest and abdomen, and determination of serum levels of HCG and alpha-fetoprotein.
Patients often present with extensive bone marrow involvement, mediastinal mass, adenopathy, CNS involvement, and splenomegaly. [1] The symptoms can appear acutely or develop progressively over time. The most common clinical feature among patients is the proliferation of malignant clones, suppressing normal haematopoiesis and resulting in a ...
Here’s what could be behind your left breast pain. ... This Serious Condition Could Cause Pain Under Your Breast. Madeleine Haase, Korin Miller. October 28, 2024 at 4:55 PM
Pain on the upper right side can also be a sign of a kidney issue. We have two kidneys, one on either side of the body, and the right kidney is situated just under the liver.
The main symptom is usually severe central chest pain. Other symptoms include laboured breathing, voice distortion (as with helium) and subcutaneous emphysema, specifically affecting the face, neck, and chest. [4] Pneumomediastinum can also be characterized by the shortness of breath that is typical of a respiratory system problem.