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The chorionic villi are at first small and non-vascular. 13–15 days: trophoblast only [1] Secondary: The villi increase in size and ramify, while the mesoderm grows into them. 16–21 days: trophoblast and mesoderm [1] Tertiary: Branches of the umbilical artery and umbilical vein grow into the mesoderm, and in this way the chorionic villi are ...
Immature chorionic villi are larger and have more central blood vessels; thus, the diffusion distance for gas and nutrient exchange is larger and, therefore, placental function is impaired. Low mag. High mag.
Chorionic villi (right of image) and cartilage, i.e. fetal parts (left of image). H&E stain. Products of conception, abbreviated POC, is a medical term used for the tissue derived from the union of an egg and a sperm. It encompasses anembryonic gestation (blighted ovum) which does not have a viable embryo.
During a molar pregnancy, the uterus contains a growing mass characterized by swollen chorionic villi, resembling clusters of grapes. [2] The occurrence of a molar pregnancy can be attributed to the fertilized egg lacking an original maternal nucleus. As a result, the products of conception may or may not contain fetal tissue.
Massive perivillous fibrin deposition (MPFD, or MFD) refers to excessive deposition of fibrous tissue around the chorionic villi of the placenta.It causes reduced growth of the foetus, and leads to miscarriage in nearly 1 in 3 pregnancies affected.
A complete miscarriage is when all products of conception have been expelled; these may include the trophoblast, chorionic villi, gestational sac, yolk sac, and fetal pole ; or later in pregnancy the foetus, umbilical cord, placenta, amniotic fluid, and amniotic membrane.
Micrograph showing chorionic villi-the tissue that is collected in CVS. During pregnancy, women can be screened by chorionic villus sampling and amniocentesis to detect trisomy 16. With the advent of noninvasive techniques for detecting aneuploidy , prenatal screening with tests using Next Generation Sequencing can be utilised before invasive ...
The risk of miscarriage in CVS is estimated to be potentially as high as 1–2%. However some recent research has suggested that only a very small number of miscarriages that occur after CVS are a direct result of the procedure. [6] Apart from a risk of miscarriage, there is a risk of infection and amniotic fluid leakage.