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Nystatin, sold under the brand name Mycostatin among others, is an antifungal medication. [1] It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. [1]
The only polyene antifungal available topically is nystatin, which works by binding to ergosterol thus disrupting the integrity of the fungal cell membrane. Similar to azoles, allylamines disrupt the fungal cell wall synthesis through inhibition of the squalene epoxidase enzyme that converts squalene into ergosterol.
It is commonly available without a prescription in various dosage forms, such as a topical cream, ointment, or vaginal suppository. [2] [7] It is also available as an oral troche or throat lozenge as a prescription only. Topically, clotrimazole is used for vulvovaginal candidiasis (yeast infection) or yeast infections of the skin. For ...
Nifuratel (brand name Macmiror, or — in combination with nystatin, — Macmiror Complex) is a drug used in gynecology. It is a local antiprotozoal and antifungal agent that may also be given orally. Nifuratel is not approved for use in the United States.
Not only can they be paired, but they work even better as a duo. A 2019 meta-analysis found that the combo of oral finasteride and minoxidil topical solution worked better than either one used ...
In the United Kingdom, behind-the-counter medicines are called pharmacy medicines which can only be sold in registered pharmacies, by or under the supervision of a pharmacist. These medications are designated by the letter P on the label. [21] The range of medicines available without a prescription varies from country to country.
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