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Cerebral hypoxia is typically grouped into four categories depending on the severity and location of the brain's oxygen deprivation: [20] Aneurysm in a cerebral artery, one cause of hypoxic anoxic injury (HAI). Diffuse cerebral hypoxia – A mild to moderate impairment of brain function due to low oxygen levels in the blood.
So, the researchers used their machine, called BrainEx, to pump a mixture of preserving agents and drugs into the dead pig brain, targeting pathways typically damaged due to a loss of oxygen. The ...
Over time, brain death became the more popular definition of biological death, and doctors codified this view in a 2019 position statement by the American Academy of Neurology.
Brain ischemia is a condition in which there is insufficient bloodflow to the brain to meet metabolic demand. [1] This leads to poor oxygen supply or cerebral hypoxia and thus leads to the death of brain tissue or cerebral infarction/ischemic stroke. [2] It is a sub-type of stroke along with subarachnoid hemorrhage and intracerebral hemorrhage. [3]
Brain death is used as an indicator of legal death in many jurisdictions, [6] but it is defined inconsistently and often confused by the public. [7] Various parts of the brain may keep functioning when others do not anymore, and the term "brain death" has been used to refer to various combinations.
Brain ischemia is insufficient blood flow to the brain, and can be acute or chronic. Acute ischemic stroke is a neurological emergency typically caused by a blood clot blocking blood flow in a vessel in the brain. [15] Chronic ischemia of the brain may result in a form of dementia called vascular dementia. [16]
Other factors in secondary damage are breakdown of the blood–brain barrier, edema, ischemia and hypoxia. [15] Ischemia is one of the leading causes of secondary brain damage after head trauma. [9] Similar mechanisms are involved in secondary injury after ischemia, trauma, and injuries resulting when a person does not get enough oxygen. [5]
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