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Signs of hyperestrogenism may include heightened levels of one or more of the estrogen sex hormones (usually estradiol and/or estrone), lowered levels of follicle-stimulating hormone and/or luteinizing hormone (due to suppression of the hypothalamic–pituitary–gonadal axis by estrogen), and lowered levels of androgens such as testosterone (generally only relevant to males). [1]
Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
Around 10–40% of males with Graves' disease (a common form of hyperthyroidism) experience gynecomastia. [26] Increased conversion of testosterone to estrogen by increased aromatase activity, [7] increased levels of SHBG and increased production of testosterone and estradiol by the testes due to elevated levels of LH cause the gynecomastia ...
Signs And Symptoms Related To High Estrogen. Here are some of the common indicators of conditions that may be associated with high estrogen, according to Dr. Woo and Dr. Guichard.
“Before menopause, the main hormone is estrogen, and after menopause, androgens like testosterone become more prevalent,” Stanhiser says. In that case, can testosterone treat menopause symptoms?
Over on the male side, Dr. Primack says that obesity is often the cause of male breast growth. ... “Male breast growth is often caused by an imbalance of estrogen levels. This can result in ...
Anabolic steroids may also be a major cause of high androgen and estrogen functional activity. Other possible causes include head injuries and brain inflammatory diseases. [3] Hypergonadism may contribute to symptoms such as precocious puberty and abnormal facial hair growth in females. [4]
For women, a drop in estrogen can cause weight gain, particularly in the abdomen (aka menopause belly). For men, low testosterone is linked to an increase in fat mass. Men with obesity are more ...