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Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.
However, some do not act via inhibition of this enzyme, and instead act via other, poorly elucidated mechanisms. Unlike acetaldehyde dehydrogenase inhibitors and other disulfiram-like drugs, alcohol dehydrogenase inhibitors such as fomepizole (brand name Antizol) inhibit the metabolism of alcohol into acetaldehyde, thereby increasing and ...
Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [ 1 ] [ 2 ] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [ 3 ] [ 4 ] use).
In a 2015 story on TODAY.com, professor and epidemiologist at Harvard T.H. Chan School of Public Health, said that daily fish consumption for most people is "fine." Mercury is another concern when ...
Red Tide caused by dinoflagellates. Picture taken off the coast of San Diego, California. Neurotoxic shellfish poisoning (NSP) is caused by the consumption of brevetoxins, which are marine toxins produced by the dinoflagellate Karenia brevis (among several others). These toxins can produce a series of gastrointestinal and neurological effects.
What Type of Fish Do You Eat Most Often for Heart Health? Bet you saw this one coming: Cardiologists were basically unanimous in saying that salmon is the most heart-healthy fish thanks to its ...
Many varieties of fish, particularly cold-water oily fish like salmon, are rich in omega-3 fatty acids, “healthy” fats that support heart, brain and eye health.
Human activities affect marine life and marine habitats through overfishing, habitat loss, the introduction of invasive species, ocean pollution, ocean acidification and ocean warming. These impact marine ecosystems and food webs and may result in consequences as yet unrecognised for the biodiversity and continuation of marine life forms.