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X-ray of polydactylic left hand a Wikipedia:Featured picture. High-quality X-ray, clearly illustrates the topic polydactyly. Also makes me think, "you have six fingers on your right hand; someone was looking for you..." grendel|khan 22:33, 2004 Dec 25 (UTC) Nominate and support. grendel|khan 22:33, 2004 Dec 25 (UTC) Comment.
Polydactyly 01 Lhand AP.jpg licensed with Cc-by-sa-3.0-migrated, GFDL 2005-04-25T19:19:50Z Magnus Manske 891x1077 (122172 Bytes) Conversion of a DICOM-format X-ray from a patient of [[:User:Drgnu23]], a ten year old male. This is the patient's left hand, anterior-posterior view. Identifying tags and such have been stripped. The image is his ...
Polydactyly also occurs in modern extant reptiles [82] and amphibians. [83] Polydactyly was a non-pathological, reacquired condition in extinct marine reptiles such as ichthyosaurs and hupehsuchians, some of which containing upwards of ten digits within their flippers. [84]
The pathophysiology of cleft hand is thought to be a result of a wedge-shaped defect of the apical ectoderm of the limb bud (AER: apical ectodermal ridge). [6] Polydactyly, syndactyly and cleft hand can occur within the same hand, therefore some investigators suggest that these entities occur from the same mechanism. [6]
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The variant of MS that fuses the 4th and 5th metacarpals is caused by X-linked recessive mutations (alterations or duplications) in the FGF16 gene, in chromosome X. [10]It is a feature of various rare disorders such as Apert's syndrome, and can occur alongside other isolated congenital hand/foot malformations including syndactyly, cleft hand, metatarsal synostosis, and polydactyly.
Synpolydactyly is a combination of syndactyly and polydactyly. This image shows the hand morphology of an individual with polydactyly. SPD is inherited in an autosomal dominant pattern, meaning that an individual only needs to inherit one copy of the affected gene, also known as an allele, from either parent to potentially develop the condition.