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Cryptorchidism, also known as undescended testis, is the failure of one or both testes to descend into the scrotum. The word is from Ancient Greek κρυπτός (kryptos) ' hidden ' and ὄρχις (orchis) ' testicle ' .
Cryptorchidism, or "undescended testicles", is when the testicle does not descend into the scrotum of an infant boy. [30] Testicular enlargement is an unspecific sign of various testicular diseases, and can be defined as a testicular size of more than 5 cm × 3 cm (short axis). [42]
One testicle not descending into the scrotum during normal embryonic or fetal development (3–4% of 'normal' live births), also known as undescended testis or cryptorchidism. In this case the testis is within the abdominal cavity, somewhere along the normal route of descent – most commonly, within the inguinal canal .
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Cryptorchidism (undescended testes) are observed in INSL3-null male mice. This implicates INSL3 as a key hormone in the growth and differentiation of the gubernaculum to allow transabdominal migration. Higher testicular temperatures associated with cryptorchidism is associated with reduced fertility. [1]
The most common presentation of testicular cancer is a hard, painless lump which can be felt on one of the testis. It is either noticed by a clinician during a routine examination, or the patient themselves. Risk factors for TC include cryptorchidism, family history, and previous testicular cancer. A diagnosis is confirmed in various ways.
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Orchiopexy is performed in the event of testicular torsion, a urologic emergency presenting with intense pain and often without inciting injury. [citation needed]While neonatal torsion occurs with no anatomic defect to account for its occurrence (occurring in utero or shortly after birth), adult torsion results from a bilateral congenital anomaly often called a "bell-clapper deformity", where ...