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University Medical Center, the teaching hospital of Texas Tech University Health Sciences Center in Lubbock. The Texas Tech University Health Sciences Center (TTUHSC) is a public medical school based in Lubbock, Texas, with additional campuses in Abilene, Amarillo, Dallas, and the Permian Basin. TTUHSC serves more than 100 counties in the ...
The School of Medicine (SOM) located in Lubbock, Texas was established as the Texas Tech University School of Medicine in 1969 by the 61st Texas Legislature, and the SOM first graduated Doctors of Medicine in 1974. [3] [4] The SOM has grown into the Texas Tech University Health Sciences Center (TTUHSC), and the SOM is now just one school within ...
A telomere (/ ˈ t ɛ l ə m ɪər, ˈ t iː l ə-/; from Ancient Greek τέλος (télos) ' end ' and μέρος (méros) ' part ') is a region of repetitive nucleotide sequences associated with specialized proteins at the ends of linear chromosomes (see Sequences). Telomeres are a widespread genetic feature most commonly found in eukaryotes.
When the cell does this due to telomere-shortening, the ends of different chromosomes can be attached to each other. This solves the problem of lacking telomeres, but during cell division anaphase, the fused chromosomes are randomly ripped apart, causing many mutations and chromosomal abnormalities. As this process continues, the cell's genome ...
Shelterin (also called telosome) is a protein complex known to protect telomeres in many eukaryotes from DNA repair mechanisms, as well as to regulate telomerase activity. In mammals and other vertebrates, telomeric DNA consists of repeating double-stranded 5'-TTAGGG-3' (G-strand) sequences (2-15 kilobases in humans) along with the 3'-AATCCC-5' (C-strand) complement, ending with a 50-400 ...
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As telomeres do not contain a canonical stop codon signaling the end of RNA transcription, it remains unclear exactly where transcription ceases along the telomere tracks. Similarly to most mRNAs transcribed in the nucleus, nearly all TERRA transcripts contain a 7-methylguanosine (m 7 G) cap structure at their 5' end. [ 10 ]
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