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Dutasteride (brand name Avodart) inhibits all three 5α-reductase isoenzymes and can decrease DHT levels by 95%. [9] [10] It can also reduce DHT levels in the prostate by 97 to 99% in men with prostate cancer. [11] [12] Epristeride (brand names Aipuliete, Chuanliu) is marketed in China for the treatment of benign prostatic hyperplasia.
[3] [23] Since dutasteride is an inhibitor of both type 1 and 2 5α-reductases, it could theoretically be a more effective therapy for hirsutism. However, dutasteride is not recommended for this indication due to a lack of supportive clinical evidence and a substantial risk of birth defects in female patients who inadvertently become pregnant ...
A 2015 Cochrane review found that NSAA monotherapy for prostate cancer had a greater risk of treatment discontinuation due to adverse effects than monotherapy with a GnRH agonist or surgical castration (RR = 1.82). [122] This included a greatly increased risk of breast pain (RR = 22.97) and gynecomastia (RR = 8.43). [122]
This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer.This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.
Through its more than 80 disease-specific financial assistance programs, PAN serves well over 100,000 patients each year from every US state and territory. [4] Without the PAN Foundation’s support, these patients would have faced impossible choices—with many simply going without their life-saving treatment.
Locks of Love is a 501(c)(3) nonprofit charity that provides custom-made hair prosthetics to disadvantaged children up to the age of 21 who have suffered hair loss as a result of medical conditions, such as alopecia, burn trauma, and cancer treatment. [3]
Lowering androgen levels or stopping them from getting into prostate cancer cells often makes prostate cancer shrink or grow more slowly for a time. However, this treatment needs to be combined with radiation therapy (RT) [8] because ADT itself does not eradicate the cancer; it just decreases its aggressiveness. [9]
A 2015 Cochrane review found unclear usefulness for cancer pain, [44] though other reviews have found tentative evidence of benefit. [45] [46] It is of unclear effect in hot flashes in people with breast cancer. [47] The effects of aromatherapy are unclear with no peer-reviewed research in regards to cancer treatment. [48]