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The virus causes measles, a highly contagious disease transmitted by respiratory aerosols that triggers a temporary but severe immunosuppression.Symptoms include fever, cough, runny nose, inflamed eyes and a generalized, maculopapular, erythematous rash and a pathognomonic Koplik spot seen on buccal mucosa opposite to lower 1st and 2nd molars.
Measles is caused by the measles virus, a single-stranded, negative-sense, enveloped RNA virus of the genus Morbillivirus within the family Paramyxoviridae. [ 51 ] The virus is highly contagious and is spread by coughing and sneezing via close personal contact or direct contact with secretions. [ 52 ]
Measles is seldom given as an individual vaccine and is often given in combination with rubella, mumps, or varicella (chickenpox) vaccines. [1] Below is the list of measles-containing vaccines: Measles vaccine (standalone vaccine) Measles and rubella combined vaccine ; Mumps, measles and rubella combined vaccine (MMR vaccine) [70] [73] [74]
Most recent reported cases of measles in Portugal are originally imported from other European countries (United Kingdom, France and Romania), Africa (Angola, South African and Ethiopia) and Asia (China). [144] Since 2004, Portugal reported 22 confirmed cases of measles. Virus isolates from 2005 and 2008 outbreaks belong the genotype D4. [145]
This is an accepted version of this page This is the latest accepted revision, reviewed on 20 December 2024. Combined vaccine against measles, mumps, and rubella Pharmaceutical compound MMR vaccine MMR vaccine Combination of Measles vaccine Vaccine Mumps vaccine Vaccine Rubella vaccine Vaccine Clinical data Trade names M-M-R II, Priorix, Tresivac, others Other names MPR vaccine AHFS / Drugs ...
Measles rash shown on child. Rash normally appears after 4 days. In the United States, before the measles vaccination program started in 1963, the Centers for Disease Control and Prevention (CDC) estimated that about three to four million people were infected each year, of which approximately 500,000 were reported, with 400 to 500 people dying and 48,000 being hospitalized. [2]
The human CD46 antigen is known to be the functional cellular receptor for Measles virus. [4] This type 1 integral membrane glycoprotein is a normal part of human tissue but may be overexpressed on some cancer cell types. [2] MV-NIS is the first targeted engineered virus therapy to have shown remission in published cancer clinical trials. [2] [5]
Measles is a highly contagious infectious disease, caused by the measles virus. [1] [2] It is also known as rubeola. vs Rubella and Roseola.