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Muir–Torre syndrome is a rare hereditary, autosomal dominant cancer syndrome [1]: 663 that is thought to be a subtype of HNPCC (Lynch syndrome). Individuals are prone to develop cancers of the colon, genitourinary tract, and skin lesions, such as keratoacanthomas and sebaceous tumors .
Sebaceous adenomas, in isolation, are not significant; however, they may be associated with Muir-Torre syndrome, a genetic condition that predisposes individuals to cancer. [3] It is also linked to hereditary nonpolyposis colorectal cancer (Lynch syndrome). [citation needed]
Hereditary nonpolyposis colorectal cancer (HNPCC) is a hereditary predisposition to colon cancer.. HNPCC includes (and was once synonymous with) [1] Lynch syndrome, an autosomal dominant genetic condition that is associated with a high risk of colon cancer, endometrial cancer (second most common), ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. [2]
Other SGc including those occurring outside of the head and neck region and the presentation of multiple at a time are believed to be associated with genetic defects including defects in mismatch repair genes, Muir–Torre syndrome (MTS), and familial retinoblastoma. [11] [10] [9]
Ferguson–Smith syndrome + Muir–Torre syndrome + + Nevoid basal cell carcinoma syndrome + Bazex syndrome + Rombo syndrome + Discoid lupus erythematosus + Erosive lichen planus + Lichen sclerosus + Porokeratosis + Nevus sebaceous [note 1] + Chronic non-healing wounds + Seborrheic keratosis +
Melania Trump has returned to the White House alongside her husband, President Donald Trump. Take a look at the life of America's first lady, who went from a model to a powerful world figure.
Though details (and photos) of the event are scarce, we know Beyonce wore a Vera Wang gown and the event took place at their penthouse. 8. David and Victoria Beckham (July 4, 1999)
To date, the six victims said they've received less than $500,000 of the $10.3 million R. Kelly owes them.