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Wickham striae or Wickham's striae are whitish lines visible in the papules of lichen planus and other dermatoses, typically in the oral mucosa. [1] The microscopic appearance shows hypergranulosis .
Lichen planus may be categorized as affecting mucosal or cutaneous surfaces.. Cutaneous forms are those affecting the skin, scalp, and nails. [10] [11] [12]Mucosal forms are those affecting the lining of the gastrointestinal tract (mouth, pharynx, esophagus, stomach, anus), larynx, and other mucosal surfaces including the genitals, peritoneum, ears, nose, bladder and conjunctiva of the eyes.
Striae, or "stretch marks", begin as reddish or purple lesions which can appear anywhere on the body, but are most likely to appear in places where larger amounts of fat are stored. The most common places are the abdomen (especially near the navel ), breasts, upper arms, underarms, back, thighs (both inner and outer), hips, and buttocks.
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Wickham's striae: Louis Frédéric Wickham: dermatology: lichen planus: white or greyish lines on the lichen planus lesions Widal test: Georges-Fernand Widal: microbiology: enteric fever: serum agglutination; obsolete(?) Winterbottom's sign: Thomas Masterman Winterbottom: tropical medicine: trypanosomiasis: posterior cervical chain adenopathy
Alfred Blaschko, a private practice dermatologist from Berlin, first described and drew the patterns of the lines of Blaschko in 1901. He obtained his data by studying over 140 patients with various nevoid and acquired skin diseases and transposed the visible patterns the diseases followed onto dolls and statues, then compiled the patterns onto a composite schematic of the human body.
Louis Frédéric Wickham (28 February 1861 in Paris – 14 October 1913 in Mesnil-le-Roi) was a French physician and pathologist remembered for describing Wickham striae. [1] He trained in medicine in Paris, receiving his M.D. in 1890.