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Cryptorchidism, also known as undescended testis, is the failure of one or both testes to descend into the scrotum.The word is from Ancient Greek κρυπτός (kryptos) 'hidden' and ὄρχις (orchis) 'testicle'.
Classical Roman law, that is Roman law until the end of the second century AD, did not contain the unus testis-rule according to current scholarly understanding, even though D. 22.5.12 [γ] – a passage of the Digest attributed to the early 3rd century Roman jurist Ulpian – had historically been understood as evidence for the existence of such a rule during this period.
The lower part persists as the gubernaculum testis ("scrotal ligament"). This ligament secures the testis to the most inferior portion of the scrotum, tethering it in place and limiting the degree to which the testis can move within the scrotum. Cryptorchidism (undescended testes) are observed in INSL3-null male mice.
The ectopic testis can be in the perineal region, the opposite side of the scrotum, the suprapubic region, the femoral region, or the superficial inguinal pouch. [1]The ectopic testis is initially normal, but if it is ignored after childhood, it may become small and soft, with spermatogenesis arresting and interstitial cell proliferation occurring.
The descent of the testicles consists of the opening of a connection from the testis to its final location at the anterior abdominal wall, followed by the development of the gubernaculum, which subsequently pulls and translocates the testicle down into the developing scrotum. Ultimately, the passageway closes behind the testis.
It carries with it the ductus deference, which are testicular vessels and nerves, a portion of the abdominal muscle, and lymph vessels. All of the structures remain attached to the testis and form what is known as the spermatic cord. By the time the testis is in the scrotal sac, the gubernaculum is no more than a remnant of scar like tissue. [10]
The tunica albuginea is a dense, [1] [2] blue-white [3] layer of fibrous tissue surrounding the testis. [1] [4] It is the middle of three envelopes forming the capsule of the testis; it is deep to the visceral layer of tunica vaginalis, and superficial to the tunica vasculosa testis (vascular layer of testis).
The mediastinum testis is a thick yet incomplete septum at the posterior part of the testis formed by the tunica albuginea of testis projecting into the testis at its posterior aspect where the testis is not lined by the serous membrane to allow for the attachment of the epididymis.